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Gypenoside LI
CAS No. 94987-10-7
Gypenoside LI( —— )
Catalog No. M32144 CAS No. 94987-10-7
Gypenoside LI possesses non-small cell lung carcinoma A549 cell inhibitory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 513 | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
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Biological Information
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Product NameGypenoside LI
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NoteResearch use only, not for human use.
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Brief DescriptionGypenoside LI possesses non-small cell lung carcinoma A549 cell inhibitory activity.
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DescriptionGypenoside LI possesses non-small cell lung carcinoma A549 cell inhibitory activity.
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In VitroGypenoside LI (0-80 μM) inhibits A549 cells in a dose-dependent manner. Gypenoside LI induces G2/M and arrest apoptosis in A549 cells.Gypenoside LI increases intracellular ROS level. Gypenoside LI suppressed migration of A549 cells.Gypenoside LI could obviously suppress the expression of CDK1 protein rather than CDK2 and CDK4 proteins.Gypenoside LI inhibits cell proliferation and upregulates expression of miR-128-3p in melanoma cells.Gypenoside LI (75 and 29.71 μg/mL) can induce intrinsic apoptosis along with S phase arrest. Gypenoside LI inhibited the colony formation ability of melanoma through inhibition of the Wnt/β-catenin signaling pathway.Gypenoside LI induces PARP cleavage, increased the expression of cleaved caspase-9 and BID death agonist, and downregulates the expression of FLIP (long form) and BCl-2 in the A375 and SK-MEL-28 melanoma cells. Cell Viability Assay Cell Line:A549 cells.Concentration:0-80 μM.Incubation Time:24 h.Result:Displayed the strongest activity with the IC50 values of 21.36 ± 0.78 μM.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number94987-10-7
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Formula Weight801
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Molecular FormulaC42H72O14
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (124.84 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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